Symbol Name ID |
Crebbp
CREB binding protein MGI:1098280 |
Darker colors indicate more annotations |
Human Phenotypes | Leukemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Recurrent upper respiratory tract infections |
Accessory spleen |
Polysplenia |
Recurrent infections |
Disease(s) Associated with CREBBP | ||||||||
acute lymphoblastic leukemia | ||||||||
acute myeloid leukemia | ||||||||
Rubinstein-Taybi syndrome |
Mouse Phenotypes | small thymus |
decreased thymocyte number |
enlarged spleen |
decreased double-positive T cell number |
increased double-positive T cell number |
abnormal granulocyte morphology |
increased granulocyte number |
decreased B cell number |
absent pre-B cells |
decreased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased lymphocyte cell number |
abnormal leukocyte morphology |
abnormal tumor necrosis factor level |
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Availability | Mouse Genotype | |||||||||||||||
Crebbptm1Pkb/Crebbptm1Pkb | ||||||||||||||||
CrebbpGt(U-San)112Imeg/Crebbp+ | ||||||||||||||||
Crebbptm1Dli/Crebbp+ | ||||||||||||||||
Crebbptm1Jvd/Crebbptm1Jvd Tg(MMTV-cre)4Mam/0 (conditional) |
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Crebbptm1Jvd/Crebbptm1Jvd Tg(Lck-cre)548Jxm/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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